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Complete Figure 1: mouse sample and sequencing workflow, transcript classes, sample correlations, PCA, transcript lengths, exon counts and isoform counts. — Figure 1图 1Wu et al. · Journal of Ovarian Research (2026)Wu 等 · Journal of Ovarian Research（2026） · Source出处 · CC BY-NC-ND 4.0

2026 / Journal of Ovarian ResearchResearch article研究论文

Full-length transcriptomic profiling reveals age-associated isoform remodeling and altered coding potential in the mouse ovary

Long-read RNA sequencing profiles full-length transcripts in granulosa cells and oocytes from young and aged mice. The study identifies age-associated isoform changes, alternative polyadenylation and differences in predicted coding potential.通过长读长 RNA 测序解析年轻与衰老小鼠颗粒细胞和卵母细胞的全长转录本，识别与年龄相关的异构体变化、可变多聚腺苷酸化及预测编码潜能差异。

TRANSCRIPTOME DIVERSITY转录组多样性

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2026 / bioRxivPreprint · not peer reviewed预印本 · 未经同行评审

ANCHOR: haplotype-aware allelic and isoform inference from single-cell long-read RNA sequencing with de novo variant calling

This preprint introduces a framework for variant discovery, haplotype assignment and allele-resolved isoform quantification in single-cell long-read RNA sequencing. Applications include parent-of-origin expression during mouse gastrulation; the work has not been peer reviewed.该预印本提出面向单细胞长读长 RNA 测序的变异发现、单倍型分配及等位基因分辨的异构体定量框架，并应用于小鼠原肠胚形成中的亲本来源表达分析；尚未经同行评议。

EARLY DEVELOPMENT早期发育TRANSCRIPTOME DIVERSITY转录组多样性

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